General Hospital (GH) spoilers tease Sam McCall (Kelly Monaco) is going to die soon. That much has been confirmed, as many fans lament that she has been let go from GH production after 21 years of dedicated service.

But the details of her death haven’t even inched toward any sort of reveal. So we’re left to speculate as to how it’s going to happen and who will be to blame.

Thus far, few people have moved into Sam’s orbit that aren’t normally present in her life. So it seems unlikely that her untimely death will be the result of some sort of freak accident or tragic attack. Still, we’re leaving room for that possibility as the end of her life comes into focus.

General Hospital Spoilers — Sonny Sees No Way Out

Sonny Corinthos (Maurice Benard) may not see Sam as a very big threat right now, but word on the street is that’s about to change.

He’s got no way to protect himself from persecution for FBI Agent John ‘Jagger’ Cates’ (Adam Harrington) murder but to rely on Carly Spencer’s (Laura Wright) testimony that she was with him at the time Cates was killed.

Of course, that lie hinges on whether they can convince anyone that they’re truly back together. If Sam starts to poke holes in that theory, Sonny could worry that she may expose both of them, leaving him what he thinks is no choice but to take her out.

GH Spoilers Reveal a Shock Could Be in Store

Heather Webber (Alley Mills) is potentially getting out of prison soon, if Ric Lansing (Rick Hearst) can pull enough strings to make it happen on the heels of serving up evidence that the cobalt hip implant she was given had poisoned her, causing metallosis and a string of unpredictable, violent behavior. But what if that’s all a ruse?

What is Heather is pretending to be a changed woman just to get on the outside where she’ll continue to wreak havoc? If that’s the case, Sam could be her next target.

At the same time, some fans have theorized that the end of her life might dovetail with Hamilton Finn’s (Michael Easton) storyline that has been left open-ended.

While Easton is also gone from GH production, that doesn’t mean we won’t see a fatal accident that takes Sam’s life while implicating Finn — who probably continues to go on the run if we learn he never really entered rehab and kept drinking.

General Hospital Spoilers — Dante Goes Dark

While a freak accident at the hands of a drunk driver or death via poisoned hook might blindside us, nothing would be more shocking than if the gentle man Sam loves is the person who actually does her in in the end.

Dante Falconeri (Dominic Zamprogna) has been acting slightly out of character. He’s not working as much. His partner, Harrison Chase (Josh Swickard), has been trying to, but Dante recently thwarted his attempt at doing his job when it came to his own family.

Lulu Falconeri (Alexa Havins) may be dying, and it’s weighing heavily on Dante — who can’t seem to make sense of how he loves two women at once. Will taking one of them out of the equation come as Dante suffers a mental break? Stay tuned for more GH news and spoilers to find out.